12 Best Flea and Tick Treatments for Dogs – Keep Your Pup Pest-Free! Ranked & Reviewed for 2025
Check out the 12 best flea and tick treatments for dogs that effectively eliminate pests and protect your furry friend.
FRONTLINE Plus Flea and Tick Treatment for Large Dogs
$39.98 ($13.33 / Count)Features:
Protects against fleas, ticks, and lice for 30 days; easy to apply; waterproof; safe for puppies 8 weeks+.
What We Think:
"This tried-and-true formula is a favorite among dog owners for good reason. It’s super effective and easy to apply, just once a month!"
Why You'll Love It:
"With a reputation built over 20 years, FRONTLINE delivers excellent, long-lasting protection that gives peace of mind."
FRONTLINE Plus Flea and Tick Treatment for Small Dogs
$39.98 ($13.33 / Count)Features:
Targets fleas, ticks, and lice for 30 days; suitable for puppies; waterproof & easy to apply.
What We Think:
"Your small dog deserves the same kick-butt protection as larger breeds. This one’s lightweight yet powerful enough to handle even the toughest flea problems."
Why You'll Love It:
"Trusted for years, it’s like having a superhero shield against those pesky parasites."
PetArmor Plus Flea Treatment for Small Dogs
$24.93Features:
Waterproof; kills fleas and ticks within 24 hours; 3-month supply.
What We Think:
"Another great option if you want reliable results for small breeds – Pets deserve the best!"
Why You'll Love It:
"Unlike others, this one just works – straightforward and effective for smaller pups!"
K9 Advantix II Flea, Tick & Mosquito Treatment
$35.68 ($17.84 / Count)Features:
Protects large dogs from fleas, ticks, and mosquitoes; easy topical treatment; waterproof.
What We Think:
"This is a complete protection package! Not only does it tackle fleas and ticks, but it also sends mosquitoes packing."
Why You'll Love It:
"Dog days just got better with K9 Advantix II – a must-have for outdoor adventures!"
PetArmor CAPACTION Oral Flea Treatment for Dogs
$26.94 ($4.49 / Count)Features:
Fast-acting; kills fleas in 30 minutes; safe for multiple pets; no prescription needed.
What We Think:
"Want a quick fix? These tablets are a lifesaver for dogs who already have fleas and need immediate relief."
Why You'll Love It:
"Perfect for sudden infestations, they are super easy to use and dogs love the taste!"
Advantus Soft Chewable Flea Treatment
$32.18 ($4.60 / Count)Features:
Starts killing fleas in one hour; suitable for various dog sizes; chewable form for easy administration.
What We Think:
"Chewables make treating fleas oh-so-simple! No fuss, just chew and done!"
Why You'll Love It:
"Your pup will love the soft chew, and you’ll love how fast it works!"
Flea and Tick Prevention Pills for Dogs
$22.95 ($0.14 / Count)Features:
Natural ingredients; tasty chewables; suits all breeds; vet-recommended.
What We Think:
"Finally, a natural option that doesn’t compromise on results! These chews make flea prevention a breeze!"
Why You'll Love It:
"Your furry friend won’t mind taking these, and you’ll feel good about the natural ingredients!"
Capstar Fast-Acting Oral Flea Treatment for Dogs
$39.98 ($6.66 / Count)Features:
Starts killing fleas in 30 minutes; perfect for small dogs; can be given daily if needed.
What We Think:
"If you’re in a panic over a flea infestation, Capstar is your go-to! It’s fast and effective!"
Why You'll Love It:
"Watch fleas fall off – it’s that fast! Your pup will thank you for the quick relief!"
Woyamay Flea and Tick Prevention Chewables
$25.99 ($0.13 / Count)Features:
Delicious chicken flavor; natural ingredients; 200 soft chews per container.
What We Think:
"These treats double as preventative care – yum! Who said flea prevention can’t be tasty?"
Why You'll Love It:
"Feeding your dog these treats is like giving them a break from pests – and they’ll love it!"
Amazon Basics Flea and Tick Topical Treatment for Large Dogs
$18.63Features:
Effective for up to 30 days; protects against various pests; easy monthly application.
What We Think:
"Who knew you could get solid, effective flea treatment without the brand name price?"
Why You'll Love It:
"Budget-friendly and reliable – you'll love this option that won’t break the bank!"
Vet's Best Flea and Tick Spot-on Drops
$22.81Features:
Plant-based formula; suitable for large dogs; 4 month supply.
What We Think:
"This provides a gentle approach to pest protection that’s still effective."
Why You'll Love It:
"Feel good about using a natural product on your furry friends – it's a win-win!"